Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXRHDL)

Drug Name
RG7418 Drug Info
Synonyms BI204
Indication
Disease Entry ICD 11 Status REF
Arteriosclerosis BD40 Discontinued in Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMXRHDL

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lectin-like oxidized LDL receptor (OLR1) TTKSND3 OLR1_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Lectin-like oxidized LDL receptor (OLR1) DTT OLR1 4.995 4.194 5.326 4.129
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Arteriosclerosis
ICD Disease Classification BD40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Lectin-like oxidized LDL receptor (OLR1) DTT OLR1 3.35E-01 -0.08 -0.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019399)
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.