Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY2OVL)

Drug Name

4-(3-hydroxy-benzylideneamino)-benzenesulfonamide Drug Info

Synonyms

CHEMBL270243; 66667-57-0; NSC722923; AC1L8PAB; CBDivE_016053; 4-[(3-hydroxyphenyl)methylideneamino]benzenesulfonamide; CTK1H9643; CTK7J9950; DTXSID20328076; BDBM50371761; AKOS030585458; MCULE-4187647437; NSC-722923; SR-01000199564; SR-01000199564-1; 4-[(3-Hydroxy-benzylidene)-amino]-benzenesulfonamide; Benzenesulfonamide, 4-[[(3-hydroxyphenyl)methylene]amino]-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 405560
CAS Number: CAS 66667-57-0
TTD Drug ID: DMY2OVL

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase 2 (COX-2)	TTVKILB	PGH2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin G/H synthase 2 (COX-2)	DTT	PTGS2	7.93E-04	-0.29	-0.34

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides. Bioorg Med Chem. 2008 Mar 1;16(5):2697-706.