Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY8LDT)

Drug Name

2,6-di-t-butylphenol Drug Info

Synonyms

2,6-DI-TERT-BUTYLPHENOL; 128-39-2; 2,6-Di-t-butylphenol; 2,6-Bis(tert-butyl)phenol; 2,6-Bis(1,1-dimethylethyl)phenol; Phenol, 2,6-bis(1,1-dimethylethyl)-; 2,6-ditert-butylphenol; 2,6 Di-tert-butylphenol; Ethanox 701; Isonox 103; Ethyl 701; Ethyl AN 701; Hitec 4701; Phenol, 2,6-di-tert-butyl-; 2,6-Bis(t-butyl)phenol; NSC 49175; AN 701; CCRIS 5828; UNII-21294V58PF; HSDB 5616; 2,6-(1,1-Dimethylethyl)phenol; EINECS 204-884-0; MFCD00008820; 2,6-di-tert.-butylphenol; 2,6-Di-tert-butyl-phenol; AI3-26293; CHEMBL281071

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 31405
ChEBI ID: CHEBI:131421
CAS Number: CAS 128-39-2
TTD Drug ID: DMY8LDT

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15;17(8):3207-11.