Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYJGZ4)

Drug Name

(+/-)-2-p-tolylchroman-4-one Drug Info

Synonyms

4'-methylflavanone; CHEMBL596690; (+/-)-2-p-tolylchroman-4-one; AC1MCXMJ; Oprea1_810740; Oprea1_128105; SCHEMBL1890733; MolPort-003-699-848; HITISLKGAFZTFZ-UHFFFAOYSA-N; 2-(4-methylphenyl)chroman-4-one; BDBM50310196; AKOS003614932

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2802466
TTD Drug ID: DMYJGZ4

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1273-9.