Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYW5JX)

• Drug Name: ANALOG OF DYNORPHIN A Drug Info
• Synonyms: Dynorphin A (1-13); 72957-38-1; Analog of Dynorphin A; UNII-VFC23V742Z; Porcine dynorphin A(1-13); dynorphin (1-13); VFC23V742Z; CHEMBL405618; Dinorphin A (1-13); Dynorphin 1-13; dynorphin A(1-13); BDBM50241435; dynorphin A 1-13; 1-13-Dynorphin A (swine); Dynorphin A1-13; YGGFLRRIRPKLK; YGGFLRRXRPKLK; Dynorphin-(1-13); DYNORPHIN(1-13)-OH; BDBM224024; BDBM214798; L-Lysine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-; NCGC00163681-02; NCGC00163681-01; 957H381

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 25075996
  CAS Number: CAS 72957-38-1
  TTD Drug ID: DMYW5JX

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Opioid receptor delta (OPRD1)	TT27RFC	OPRD_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Opioid receptor delta (OPRD1)	DTT	OPRD1	2.848	2.263	1.536	2

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Opioid receptor delta (OPRD1)	DTT	OPRD1	5.52E-01	0.03	0.23

References

• [1] Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs. J Med Chem. 1993 Mar 19;36(6):750-7.