Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZCA15)

Drug Name

Cynooxide anion Drug Info

Synonyms

Fulminic acid; formonitrile oxide; Knallsaeure; HCNO; Hydrogen cyanide N-oxide; H-C#NO; formonitrile-N-oxide; [C(H)NO]; [CH(NO)]; (methylidyneammoniumyl)oxidanide; methylidyne(oxo)-lambda(5)-azane; hydrido(oxidonitrato-N)carbon; hydrido(nitrosyl-kappaN)carbon; CHEMBL185198; CHEBI:29813; 51060-05-0; Cynooxide anion; Formnitrile oxide; AC1LAVEA; CTK1G9581; DTXSID30334603; BDBM50152965; formonitrile oxideformonitrile-N-oxidehydrido(nitrosyl-kappaN)carbonhydrido(oxidonitrato-N)carbon

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 521293
ChEBI ID: CHEBI:29813
CAS Number: CAS 506-85-4
TTD Drug ID: DMZCA15

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase I (CA-I)	TTHQPL7	CAH1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase I (CA-I)	DTT	CA1	5.564	11.952	6.146	7.235

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase I (CA-I)	DTT	CA1	5.23E-14	-0.11	-0.41

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4563-7.