Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZK4DL)

Drug Name

1,8-Dichloro-10H-anthracen-9-one Drug Info

Synonyms

1,8-Dichloro-10H-anthracen-9-one; CHEMBL122022; 50259-93-3; NSC162539; 1,8-Dichloroanthrone; AC1Q3KGA; AC1L9O6M; SCHEMBL7103871; CTK1H2907; DTXSID70329816; ZINC393214; BDBM50060867; AKOS024331862; NSC-162539; MCULE-9362278595

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 424114
CAS Number: CAS 50259-93-3
TTD Drug ID: DMZK4DL

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Arachidonate 5-lipoxygenase (5-LOX)	TT2J34L	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.15E-01	-0.06	-0.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity. J Med Chem. 1997 Nov 7;40(23):3773-80.