Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZLRY2)

Drug Name
Glucagon-like peptide-1 analog Drug Info
Synonyms GLP-1 analog (type 2 diabetes), Arisaph; Glucagon-like peptide-1 analog (type 2 diabetes); Glucagon-like peptide-1 analog (type 2 diabetes), Arisaph
Indication
Disease Entry ICD 11 Status REF
Non-insulin dependent diabetes 5A11 Investigative [1]
Cross-matching ID
TTD Drug ID
DMZLRY2

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon-like peptide 1 receptor (GLP1R) TTVIMDE GLP1R_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glucagon-like peptide 1 receptor (GLP1R) DTT GLP1R 2 2.848 3.472 2.963
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Non-insulin dependent diabetes
ICD Disease Classification 5A11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucagon-like peptide 1 receptor (GLP1R) DTT GLP1R 1.25E-01 0.17 1.26
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).