Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZR94D)

Drug Name

1-(4-ethoxyphenyl)propan-2-amine Drug Info

Synonyms

4-Ethoxyamphetamine; dl-p-Ethoxyamphetamine; 129476-58-0; 1-(4-ethoxyphenyl)propan-2-amine; CHEMBL161985; 135014-85-6; 1-(4-ethoxyphenyl)prop-2-ylamine; Para-Ethoxyamphetamine; Benzeneethanamine, 4-ethoxy-alpha-methyl-; AC1L2OHT; ACMC-1BZ3A; Benzeneethanamine, 4-ethoxy-alpha-methyl-, (+-)-; SCHEMBL2553013; CTK0H5621; CCAMEVFYMFXHEN-UHFFFAOYSA-N; BDBM50005270; AKOS016298265; AKOS017269155; AKOS000155579; 1-(4-Ethoxyphenyl)-2-propanamine #; 2-(4-Ethoxy-phenyl)-1-methyl-ethylamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 125379
CAS Number: CAS 129476-58-0
TTD Drug ID: DMZR94D

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type A (MAO-A)	TT3WG5C	AOFA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type A (MAO-A)	DTT	MAOA	7.207	8.159	9.043	7.711

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type A (MAO-A)	DTT	MAOA	8.14E-01	0.05	0.1

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors. Bioorg Med Chem. 2009 Mar 15;17(6):2452-60.