General Information of Drug (ID: DMZW0YO)

Drug Name
IM-023911 Drug Info
Synonyms
IM-023911; CHEMBL193342; AC1NQ014; A2595/0110399; MolPort-002-710-895; ZINC3672574; BDBM50173049; STK765418; AKOS001757037; MCULE-3428588247; 4-[4-[4-[chloro(difluoro)methoxy]anilino]phthalazin-1-yl]benzamide; 4-(4-{4-[chloro(difluoro)methoxy]anilino}-1-phthalazinyl)benzamide; 4-{4-[4-(Chloro-difluoro-methoxy)-phenylamino]-phthalazin-1-yl}-benzamide; 4-[4-({4-[chloro(difluoro)methoxy]phenyl}amino)phthalazin-1-yl]benzamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5187941
TTD Drug ID
DMZW0YO

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 2 (KDR) DTT KDR 1.98E-01 0.11 0.2
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Arylphthalazines: identification of a new phthalazine chemotype as inhibitors of VEGFR kinase. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4696-8.