Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM03GDJ)

Drug Name

Pepinemab Drug Info

Synonyms

VX15/2503

Indication

Disease Entry	ICD 11	Status	REF
Squamous head and neck cell carcinom	2D60.0	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Semaphorin-4D (SEMA4D)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
VX-15	DMLWM4G	Huntington disease	8A01.10	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT04815720) Pepinemab in Combination With Pembrolizumab in Advanced, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (KEYNOTE B84). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Vaccinex.
3	Safety, Pharmacokinetics, and Pharmacodynamics of a Humanized Anti-Semaphorin 4D Antibody, in a First-In-Human Study of Patients with Advanced Soli... Clin Cancer Res. 2016 Feb 15;22(4):827-36.