General Information of Drug (ID: DM068CY)

Drug Name
EUPATORIOPICRIN Drug Info
Synonyms
Eupatoriopicrin; CHEMBL221283; 6856-01-5; Eupatoriopicrine; AC1NQYHY; CHEBI:4937; BDBM50194428; C09442; [(3aR,4R,6E,10E,11aR)-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E)-4-hydroxy-2-(hydroxymethyl)but-2-enoate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5281461
ChEBI ID
CHEBI:4937
CAS Number
CAS 6856-01-5
TTD Drug ID
DM068CY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fosfomycin DMVGPMX Bacterial infection 1A00-1C4Z Approved [2]
Uridine-Diphosphate-N-Acetylglucosamine DMEQSTP Discovery agent N.A. Investigative [3]
RWJ-3981 DMBVLCQ Gram-positive bacterial infection 1B74-1G40 Investigative [4]
RWJ-140998 DMP7SI9 Gram-positive bacterial infection 1B74-1G40 Investigative [4]
Aminomethylcyclohexane DMNX9FC Discovery agent N.A. Investigative [5]
CNICIN DMEVM0J Discovery agent N.A. Investigative [1]
L-Iso-Aspartate DM26AB4 Discovery agent N.A. Investigative [5]
Cyclohexylammonium Ion DMYQH2N Discovery agent N.A. Investigative [5]
CYNAROPICRIN DMG0PHU Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial UDP-N-acetylglucosamine carboxyvinyltransferase (Bact murA) TTICX3S MURA_ECOLI Inhibitor [1]

References

1 Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5605-9.
2 Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem. 2005 Feb 4;280(5):3757-63.
3 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
4 Emerging drugs for bacterial urinary tract infections. Expert Opin Emerg Drugs. 2005 May;10(2):275-98.
5 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.