Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0EZWI)

Drug Name

MDX-1100 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Crohn disease	DD70	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting C-X-C motif chemokine 10 (CXCL10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BMS-936557	DMUTS1W	Immune System disease	4A01-4B41	Phase 2	[2]
NI-0801	DMRQUH4	Autoimmune diabetes	5A10	Phase 2	[3]
Anti-IP10	DMVRNAO	Crohn disease	DD70	Phase 2	[2]
JT02	DMXTKCR	Inflammatory bowel disease	DD72	Phase 2	[4]
NG-641	DMITVHM	Solid tumour/cancer	2A00-2F9Z	Phase 1	[5]
N-Methylleucine	DM9AGCV	Discovery agent	N.A.	Investigative	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum. 2012 Jun;64(6):1730-9.
2	Anti-IP-10 antibody (BMS-936557) for ulcerative colitis: a phase II randomised study. Gut. 2014 Mar;63(3):442-50.
3	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029267)
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	Clinical pipeline report, company report or official report of PsiOxus Therapeutics.
6	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.