Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0HCG6)

Drug Name

5-bromo orotate Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Plasmodium Dihydroorotase (Malaria dho)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Orotate	DMMB29S	Discovery agent	N.A.	Investigative	[1]
Lysine Nz-Carboxylic Acid	DMW1YK3	Discovery agent	N.A.	Investigative	[2]
Dihydroorotate	DM76BGZ	Discovery agent	N.A.	Investigative	[2]
5-Fluoro orotate	DMLSC10	Discovery agent	N.A.	Investigative	[1]
N-Carbamoyl-L-Aspartate	DMJ13TR	Discovery agent	N.A.	Investigative	[2]
5-iodo orotate	DMDKFIO	Discovery agent	N.A.	Investigative	[1]
5-methyl orotate	DMYNFIP	Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium Dihydroorotase (Malaria dho)	TT09NOX	A9CSR1_PLAFA	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase. Biochem Pharmacol. 1992 Mar 17;43(6):1295-301.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.