Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0VXIM)

Drug Name

TJ003234 Drug Info

Synonyms

TJ003234 mab

Indication

Disease Entry	ICD 11	Status	REF
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 1/2	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

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Drug(s) Targeting HUMAN colony-stimulating factor (GM-CSF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lenzilumab	DMSRIT4	Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 3 Trial	[2]
Otilimab	DM1AQLW	Rheumatoid arthritis	FA20	Phase 2 Trial	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN colony-stimulating factor (GM-CSF)	TTPZGYX	CSF2_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04351152) Phase 3 Study to Evaluate Efficacy and Safety of Lenzilumab in Hospitalized Patients With COVID-19 Pneumonia. U.S. National Institutes of Health.
2	The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19. J Autoimmun. 2020 Apr 17:102468.