General Information of Drug (ID: DM1CWU7)

Drug Name
Heteroaryl-carboxamide derivative 11 Drug Info
Synonyms PMID29171765-Compound-Figure2
Cross-matching ID
TTD Drug ID
DM1CWU7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bortezomib DMNO38U Leukemia Approved [2]
Ecallantide DMOF2C6 Retina venous occlusion 9B74.1 Approved [3]
Cetraxate DMSP4JX Peptic ulcer DA61 Approved [4]
LM-030 DMSJOE3 Congenital ichthyosiform erythroderma EC20.02 Phase 2 [5]
Benzoxazinone derivative 2 DM4FHTG N. A. N. A. Patented [1]
Benzyl amine derivative 1 DMOU84B N. A. N. A. Patented [1]
Benzyl amine derivative 2 DMFK7EL N. A. N. A. Patented [1]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Kallikrein-related peptidase (KLK) TT5L2VC NOUNIPROTAC Inhibitor [1]

References

1 Serine protease inhibitors to treat inflammation: a patent review (2011-2016).Expert Opin Ther Pat. 2018 Feb;28(2):93-110.
2 Characterization of a class of peptide boronates with neutral P1 side chains as highly selective inhibitors of thrombin. J Med Chem. 1995 Apr 28;38(9):1511-22.
3 Ecallantide (DX-88), a plasma kallikrein inhibitor for the treatment of hereditary angioedema and the prevention of blood loss in on-pump cardiothoracic surgery. Expert Opin Biol Ther. 2008 Aug;8(8):1187-99.
4 A new broad spectrum inhibitor of esteroproteases, 4-(2-carboxyethyl) phenyl-trans-4-aminomethyl cyclohexane carboxylate hydrochloride (DV 1006). Tohoku J Exp Med. 1972 Mar;106(3):233-48.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)