Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1UIQP)

Drug Name

SAFIRONIL Drug Info

Synonyms

Hoe-277; Safironil; N,N'-Bis(3-methoxypropyl)pyridine-2,4-dicarboxamide

Indication

Disease Entry	ICD 11	Status	REF
Transplant rejection	NE84	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Prolyl 4-hydroxylasesubunit alpha-1 (P4HA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lufironil	DMCKNBA	Liver cirrhosis	DB93.1	Phase 2	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prolyl 4-hydroxylasesubunit alpha-1 (P4HA1)	TTNH25W	P4HA1_HUMAN	Modulator	[1]

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References

1	Antifibrogenic therapies in chronic HCV infection. Curr Drug Targets Infect Disord. 2001 Aug;1(2):227-40.
2	Interference in clinical laboratory tests, with special regard to the bilirubin assay: effects of a metabolite of the new prolyl 4-hydroxylase inhibitor, Lufironil. Eur J Clin Chem Clin Biochem. 1994Jul;32(7):515-20.