Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1Z5W8)

Drug Name

ISIS 147788 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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Drug(s) Targeting APOB messenger RNA (APOB mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mipomersen	DMGSRN1	Familial hypercholesterolemia	5C80.00	Approved	[2]
TKM-ApoB	DM2M47Y	Hypercholesterolaemia	5C80.0	Phase 4	[3]
ISIS 147483	DMNMXKC	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	US patent application no. 7,407,943, Antisense modulation of apolipoprotein B expression.
2	Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
3	Current Progress of siRNA/shRNA Therapeutics in Clinical Trials. Biotechnol J. 2011 September; 6(9): 1130-1146.