Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2HVU8)

Drug Name

PMID24673130C26 Drug Info

Synonyms

GTPL8134; BDBM50011536

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting MEK kinase kinase 4 (MAP4K4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BDBM50011553	DMHNYQU	N. A.	N. A.	Patented	[2]
6-Phenylquinazolin-4-amine	DMV5XR7	N. A.	N. A.	Patented	[2]
BDBM50011552	DMW5SD6	N. A.	N. A.	Patented	[2]
PMID23312943C21	DMOJ8QR	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization. J Med Chem. 2014 Apr 24;57(8):3484-93.
2	Aminoquinazoline and pyridopyrimidine derivatives. US9592235.
3	Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1051-5.