Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2M47Y)

Drug Name

TKM-ApoB Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hypercholesterolaemia	5C80.0	Phase 4	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting APOB messenger RNA (APOB mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mipomersen	DMGSRN1	Familial hypercholesterolemia	5C80.00	Approved	[3]
ISIS 147788	DM1Z5W8	Discovery agent	N.A.	Investigative	[4]
ISIS 147483	DMNMXKC	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT00348686) Candesartan Effectiveness Study in Pro-B Type Natriuretic Peptides (BNP). U.S. National Institutes of Health.
2	Current Progress of siRNA/shRNA Therapeutics in Clinical Trials. Biotechnol J. 2011 September; 6(9): 1130-1146.
3	Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
4	US patent application no. 7,407,943, Antisense modulation of apolipoprotein B expression.