Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM346KA)

Drug Name
Sch-900875 Drug Info
Synonyms CXCR3 antagonists (inflammatory diseases), Schering-Plough/Ligand/Merck & Co
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Investigative [1]
Cross-matching ID
PubChem CID
11997335
CAS Number
CAS 907206-98-8
TTD Drug ID
DM346KA

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting C-X-C chemokine receptor type 3 (CXCR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
T487 DMZTL7H Psoriatic disorder EA90 Discontinued in Phase 2 [2]
JT07 DMHBWOP Solid tumour/cancer 2A00-2F9Z Preclinical [3]
dioscin DM5H2W9 Hepatic fibrosis DB93.0 Preclinical [4]
kallstroemin D DM7YAE0 Discovery agent N.A. Investigative [4]
NBI-74330 DMURC6X Discovery agent N.A. Investigative [2]
hypoglaucin A DMJKIUX Discovery agent N.A. Investigative [4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-X-C chemokine receptor type 3 (CXCR3) TT1UCIJ CXCR3_HUMAN Antagonist [1]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 70).
2 Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist. J Pharmacol Exp Ther. 2005 Jun;313(3):1263-71.
3 Clinical pipeline report, company report or official report of Jyant Technologies.
4 Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3. Mol Divers. 2005;9(1-3):123-9.