Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3NBQ6)

Drug Name
rose bengal (photoactivated) Drug Info
Synonyms
CHEMBL1208422; CHEBI:87202; 2,3,4,5-tetrachloro-6-(3-hydroxy-2,4,5,7-tetraiodo-6-oxo-xanthen-9-yl)benzoic acid; 2,3,4,5-tetrachloro-6-(3-hydroxy-2,4,5,7-tetraiodo-6-oxoxanthen-9-yl)benzoic acid; NSC45732; NSC10463; NSC270091; C.I.45440; Bengalrosa; rose bengal free acid; Ak-Rose Liq 1%; Tetraiodotetrachlorofluorescein; GTPL2393; SCHEMBL1464825; AC1L196L; ZINC150338646; AN-20423; LS-194354; SR-01000939637; SR-01000939637-2
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
25474
ChEBI ID
CHEBI:87202
CAS Number
CAS 11121-48-5
TTD Drug ID
DM3NBQ6

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Inward rectifier potassium channel Kir2.3 (KCNJ4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
[14C]TEA DM6SFYH Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Inward rectifier potassium channel Kir2.3 (KCNJ4) TTXF0ZW KCNJ4_HUMAN Inhibitor (gating inhibitor) [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2393).
2 Susceptibility of cloned K+ channels to reactive oxygen species. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11796-800.
3 Cloning and expression of a novel human brain inward rectifier potassium channel. J Biol Chem. 1994 Aug 12;269(32):20468-74.