Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4DP70)

Drug Name

SAP-001 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Gout	FA25	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

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Drug(s) Targeting Glucose transporter type 9 (GLUT9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AA-193	DMB5TH3	Hyperuricaemia	5C55.Y	Discontinued in Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucose transporter type 9 (GLUT9)	TTIF3GB	GTR9_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT05690204) A Phase 2B Study to Evaluate the Efficacy and Safety in Combination With Standard of Care in Adult Subjects With Gout, and Hyperuricemia Refractory to Conventional XOI Therapy. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Shanton Pharma Shanghai, China
3	Uricosurics inhibit urate transporter in rat renal brush border membrane vesicles. Eur J Pharmacol. 1990 Oct 23;187(3):303-12.