Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4FNWO)

Drug Name
RC-01 Drug Info
Indication
Disease Entry ICD 11 Status REF
Gram-negative bacterial infection 1B74-1G40 Terminated [1]
Cross-matching ID
TTD Drug ID
DM4FNWO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Preclinical Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LpxC-1 DMV1A25 Acinetobacter baumannii infection CA40.0Y Preclinical [2]
MYRISTIC ACID DMYX0BL Discovery agent N.A. Investigative [3]
Cacodylate Ion DMK4XLD Discovery agent N.A. Investigative [4]
Palmitoleic Acid DM4W5X8 Discovery agent N.A. Investigative [4]
3-(heptyloxy)benzoic acid DMQZU9G Discovery agent N.A. Investigative [3]
BB-78484 DMFBN9O Discovery agent N.A. Investigative [5]
BB-78485 DMJKA3F Discovery agent N.A. Investigative [5]
Tu-514 DMUR0TF Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC) TT0OFWN LPXC_PSEAE Inhibitor [1]

References

1 The global preclinical antibacterial pipeline. Nat Rev Microbiol. 2020 May;18(5):275-285.
2 Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.