Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4N1SP)

Drug Name

Shigamabs Drug Info

Synonyms

C-Stx1; C-Stx2; Ca-Stx1; Ca-Stx2; Anti-Shiga toxin monoclonal antibodies, Thallion; Anti-Shiga toxin monoclonals, Sunol;Monoclonal antibodies (HUS), Sunol; Monoclonal antibodies (HUS), Thallion

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Phase 3	[1]
Haemolytic uraemic syndrome	3A21.2	Phase 2	[2]

Cross-matching ID

TTD Drug ID: DM4N1SP

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Shiga toxin 2 subunit B (Bact stxII)	TT1HYOF	Q7DJJ2_ECOLX	Modulator	[3]

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References

1	Clinical pipeline report, company report or official report of BELLUS Health Inc.
2	Company report (Bellus Health)
3	Antibacterial antibodies gain traction. Nat Rev Drug Discov. 2015 Nov;14(11):737-8.