Details of the Drug

General Information of Drug (ID: DM4N1SP)

Drug Name

Shigamabs

Synonyms

C-Stx1; C-Stx2; Ca-Stx1; Ca-Stx2; Anti-Shiga toxin monoclonal antibodies, Thallion; Anti-Shiga toxin monoclonals, Sunol;Monoclonal antibodies (HUS), Sunol; Monoclonal antibodies (HUS), Thallion

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Phase 3	[1]
Haemolytic uraemic syndrome	3A21.2	Phase 2	[2]
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Drug Type

Monoclonal antibody

Cross-matching ID

TTD ID: D07YPW

Repurposed Drugs (RPD)

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Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Shiga toxin 2 subunit B (Bact stxII)	TT1HYOF	Q7DJJ2_ECOLX	Modulator	[3]

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Molecular Interaction Atlas (MIA)

MIA Detail

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References

1	Clinical pipeline report, company report or official report of BELLUS Health Inc.
2	Company report (Bellus Health)
3	Antibacterial antibodies gain traction. Nat Rev Drug Discov. 2015 Nov;14(11):737-8.