Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4NKNK)

Drug Name

Selnoflast Drug Info

Synonyms

Selnoflast; Selnoflast [INN]; Selnoflast [USAN]; T23RPA8WA2; RO7486967; Selnoflast [USAN:INN]; RG6418; 2260969-36-4; UNII-T23RPA8WA2; WHO 11687; RO-7486967; 1-Ethyl-N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-4-piperidinesulfonamide; 1-ethyl-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]piperidine-4-sulfonamide; CHEMBL5095423; SCHEMBL20634304; GTPL12173; MFCD34579587; RG-6418; Example 6 [WO2019008025A1]; MS-26540; SY347075; HY-132831; CS-0204138; 1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea; 4-Piperidinesulfonamide, 1-ethyl-N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-; 4-Piperidinesulfonamide,1-ethyl-N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-

Indication

Disease Entry	ICD 11	Status	REF
Inflammation	1A00-CA43.1	Phase 1	[1]

Cross-matching ID

PubChem CID: 137402358
TTD Drug ID: DM4NKNK

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Caterpiller protein 1.1 (NLRP3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dapansutrile	DM7IH48	Acute gout flare	FA25.0	Phase 2	[2]
BMS-986299	DMTMUWJ	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
MCC950	DM6J2UZ	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Caterpiller protein 1.1 (NLRP3)	TT4EN8X	NLRP3_HUMAN	Inhibitor	[1]

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References

1	Clinical pipeline report, company report or official report of Roche
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	National Cancer Institute Drug Dictionary (drug name BMS-986299).
4	A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55.