Details of the Drug-Related molecule(s) Interaction Atlas

ZX-AP000068 Drug Info

DL-3-Fluoro-beta-alanine; OJQNRNQELNLWHH-UHFFFAOYSA-N; PC3387E; Propanoic acid, 3-amino-2-fluoro-; SCHEMBL637248; 2-Fluoro-beta-alanine; a-fluoro-b-alanine; a-fluoro-beta-alanine; alpha-Fluoro-beta-alanine; dl-2-Fluoro-3-alanine; (R)-3-amino-2-fluoropropanoic acid; (S)-3-Amino-2-fluoropropanoic acid; 130695-34-0; 2-Fluoro-.beta.-alanine; 2-Fluoro-beta-alanine #; 3-Amino-2-fluoropropionic acid; 3-amino-2-fluoropropanoic acid; 3821-81-6; AC1L21K0; CHEBI:80626; CHEMBL3544571; CTK8E9543; DTXSID00959160; EINECS 223-318-3

Cross-matching ID

PubChem CID

13351

ChEBI ID

CHEBI:80626

CAS Number

CAS 3821-81-6

TTD Drug ID

DM4Y0NI

INTEDE Drug ID

DR2023

General Information of Drug (ID: DM4Y0NI)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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Drug(s) Metabolized By Bile acid-CoA thioesterase (BAAT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glycine	DMIOZ29	Allergic rhinitis	CA08.0	Approved	[1]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[2]
taurine	DMVW7N3	Discovery agent	N.A.	Investigative	[1]
NSC-39851	DMMXZBK	N. A.	N. A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Bile acid-CoA thioesterase (BAAT)^{Main DME}	DERA3OF	BAAT_HUMAN	Substrate	[1]

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References

1	Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids. Methods Enzymol. 2005;400:374-94.
2	Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. J Biol Chem. 1994 Jul 29;269(30):19375-9.