Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM65UZ2)

Drug Name

NTU281 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Renal fibrosis	GC01	Preclinical	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Tissue transglutaminase (TG2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ZED1227	DMDXEN5	Coeliac disease	DA95	Phase 2	[2]
PMID26560530-Compound-13	DMKF26Z	N. A.	N. A.	Patented	[3]
PMID26560530-Compound-54	DM2X4R0	N. A.	N. A.	Patented	[3]
Triazole derivative 1	DM9QB2S	N. A.	N. A.	Patented	[3]
Acyl piperidine derivative 3	DMIDUB4	N. A.	N. A.	Patented	[3]
PMID26560530-Compound-14	DM52MIK	N. A.	N. A.	Patented	[3]
PMID26560530-Compound-1	DMSI7F2	N. A.	N. A.	Patented	[3]
PMID26560530-Compound-3	DM92OT0	N. A.	N. A.	Patented	[3]
PMID26560530-Compound-11	DMZ5UST	N. A.	N. A.	Patented	[3]
Chloroacetyl ester derivative 1	DMW4J0P	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Drugs and Targets in Fibrosis. Front Pharmacol. 2017 Nov 23;8:855.
2	Features of ZED1227: The First-In-Class Tissue Transglutaminase Inhibitor Undergoing Clinical Evaluation for the Treatment of Celiac Disease. Cells. 2022 May 17;11(10):1667.
3	Transglutaminase inhibitors: a patent review.Expert Opin Ther Pat. 2016;26(1):49-63.