Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM68QY0)

Drug Name

AR244555 Drug Info

Synonyms

AR 244555; AR-244555

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Proto-oncogene Mas (MAS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Angiotensin-(1-7)	DM76GZ0	Sarcoma	2A60-2C35	Phase 3	[3]
DSC-127	DMM0HAE	Diabetic foot ulcer	BD54	Phase 3	[3]
AVE 0991	DM9R3WT	Discovery agent	N.A.	Investigative	[4]
AR234960	DMTN10D	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7042).
2	Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection. Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H299-311.
3	New therapeutic pathways in the RAS. J Renin Angiotensin Aldosterone Syst. 2012 Dec;13(4):505-8.
4	Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney. Hypertension. 2004 Oct;44(4):490-6.