Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6AHO4)

• Drug Name: 4-Hydroxy-3-methyl-butyric acid Drug Info
• Synonyms: 4-Hydroxyisovaleric acid; 4-Hydroxyisovalerate; 4-Hydroxyisopentanoate; 4-Hydroxyisopentanoic acid; 4-hydroxy-3-methylbutanoic acid; 4-hydroxy-isovaleric acid; 77220-86-1; CHEBI:90005; 3-methyl-4-hydroxy-butanoic acid; AC1Q5V9X; AC1Q2B3C; AC1L2ZR2; SCHEMBL43435; CHEMBL353863; CTK5E4050; Butanoic acid,4-hydroxy-3-methyl-; Butanoic acid, 4-hydroxy-3-methyl-; LMFA01050399; AKOS006373039; 4-Hydroxyisovaleric acid sodium salt hydrate, analytical standard

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 131760
  ChEBI ID: CHEBI:90005
  CAS Number: CAS 77220-86-1
  TTD Drug ID: DM6AHO4
  VARIDT Drug ID: DR01075

Molecule-Related Drug Atlas

Drug(s) Targeting Gamma-hydroxybutyrate receptor (SLC52A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-Hydroxy-pent-2-enoic acid	DM5ZQK1	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-4-phenyl-butyric acid	DMDWGS9	Discovery agent	N.A.	Investigative	[1]
4-hydroxy-but-2-enoate	DMCA2XQ	Discovery agent	N.A.	Investigative	[1]
5-hydroxy-pentanoate	DMJQFZH	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-4-phenyl-but-2-enoic acid	DMIVQGW	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-3-methyl-but-2-enoic acid	DMWDBHC	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-pentanoic acid	DMDGKFV	Discovery agent	N.A.	Investigative	[1]
4-Cyclohexyl-4-hydroxy-but-2-enoic acid	DMTFL5J	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-hydroxybutyrate receptor (SLC52A2)	TT6TKEN	S52A2_HUMAN	Inhibitor	[1]

References

• [1] Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies. J Med Chem. 1988 May;31(5):893-7.