Details of the Drug-Related molecule(s) Interaction Atlas

Hydroxy-cholesten-one Drug Info

A-Hydroxy-4-cholesten-3-one; Cholest-4-en-7alpha-ol-3-one; 7 Alpha-hydroxy-4-cholesten-3-one; (7; (7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 3862-25-7; 4-Cholesten-7-alpha-ol-3-one; 7-Hydroxycholest-4-en-3-one; 7a-hydroxy-cholestene-3-one; 7alpha-Hydroxy-4-cholesten-3-one; 7alpha-Hydroxycholest-4-en-3-one; A)-7-Hydroxycholest-4-en-3-one

Cross-matching ID

PubChem CID

123743

ChEBI ID

CHEBI:17899

CAS Number

CAS 3862-25-7

TTD Drug ID

DM6IEKW

INTEDE Drug ID

DR0023

General Information of Drug (ID: DM6IEKW)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

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Drug(s) Metabolized By Aldo-keto reductase 1D1 (AKR1D1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Norethindrone acetate	DMDGCQP	N. A.	N. A.	Approved	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Aldo-keto reductase 1D1 (AKR1D1)^{Main DME}	DEVON3M	AK1D1_HUMAN	Substrate	[1]

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References

1	The effect of disease associated point mutations on 5-beta-reductase (AKR1D1) enzyme function. Chem Biol Interact. 2011 May 30;191(1-3):250-4.
2	Hormonal properties of norethisterone, 7alpha-methyl-norethisterone and their derivatives. J Steroid Biochem Mol Biol. 2000 Nov 15;74(4):213-22.