General Information of Drug (ID: DM73EPK)

Drug Name
Vapaliximab Drug Info
Synonyms Huvap; HuvapR; BTT-1002; Chimeric VAP-1 monoclonal antibody (inflammation), BioTie; Chimeric VAP-1 mAb (inflammation), BioTie/Seikagaku
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Terminated [1]
Cross-matching ID
TTD Drug ID
DM73EPK

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [3]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [4]
ASP8232 DMYK1JU Diabetic macular edema 9B71.02 Phase 2 [5]
BTT-1023 DMIEPJG Psoriasis vulgaris EA90 Phase 2 [6]
BI 1467335 DMTE3UV Diabetic retinopathy 9B71.0 Discontinued in Phase 2 [7]
Vapill DM30E56 Diabetic complication 5A2Y Investigative [8]
PSX-4206 DMVJDCM Pulmonary disease 1B10-1F85 Investigative [8]
RTU-1096 DMWVBD9 Atopic dermatitis EA80 Investigative [8]
FP-1102 DMGID4T Vascular disease BE2Z Investigative [8]
6-hydroxydopa quinone DM7M58P Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Membrane copper amine oxidase (AOC3) TT7HC21 AOC3_HUMAN Not Available [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017603)
2 Clinical pipeline report, company report or official report of Huginonline.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation. J Nucl Med. 2013 Aug;54(8):1315-9.
7 Clinical pipeline report, company report or official report of Boehringer Ingelheim.
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
9 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.