Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM73YG5)

Drug Name

SM09419 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hematologic tumour	2B33.Y	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cdc-like kinase (CLK)	TT6K9BV	CLK1_HUMAN; CLK2_HUMAN; CLK3_HUMAN; CLK4_HUMAN	Inhibitor	[1]

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References

1	SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Acute Myeloid Leukemia Models. Blood; 2019,134 (Supplement_1):1377.