Details of the Drug

General Information of Drug (ID: DM73YG5)

Drug Name

SM09419

Indication

Disease Entry	ICD 11	Status	REF
Hematologic tumour	2B33.Y	Phase 1	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cdc-like kinase (CLK)	TT6K9BV	CLK1_HUMAN ; CLK2_HUMAN ; CLK3_HUMAN ; CLK4_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Acute Myeloid Leukemia Models. Blood; 2019,134 (Supplement_1):1377.