Details of the Drug-Related molecule(s) Interaction Atlas

PhIP glucuronide Drug Info

A-D-Glucuronide; ZINC77271324; 1-Methyl-6-phenyl-N-(beta-D-glucopyranuronosyl)-1H-imidazo[4,5-b]pyridin-2-amine; 133084-70-5; 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine N-; DTXSID50747014; FT-0661931

Cross-matching ID

PubChem CID

71313317

CAS Number

CAS 133084-70-5

TTD Drug ID

DM7DWZC

INTEDE Drug ID

DR2837

General Information of Drug (ID: DM7DWZC)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Investigative Drug(s)

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Drug(s) Metabolized By Beta-glucuronidase (uidA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Diclofenac glucuronide	DMWADLM	N. A.	N. A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Beta-glucuronidase (uidA)^{Main DME}	DE9EXRN	A0A173S5S4_9FIRM	Substrate	[1]

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References

1	Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation. BMC Microbiol. 2019 May 16;19(1):99.
2	tructure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep. 2019 Jan 29;9(1):825.