General Information of Drug (ID: DM7J3K0)

Drug Name
AdcAhxArg6 Drug Info
Synonyms CHEMBL438544
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10441484
TTD Drug ID
DM7J3K0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RO-316233 DMAGLPW Discovery agent N.A. Investigative [2]
[3H]cAMP DMZRQU7 Discovery agent N.A. Investigative [3]
AdoC(Dpr)2AlaArg6 DM2TWSZ Discovery agent N.A. Investigative [4]
AdcAhxArg4NH(CH2)6NH2 DMSYMRJ Discovery agent N.A. Investigative [1]
AdcAhxArg4Lys-PEGOMe DMQ2C8X Discovery agent N.A. Investigative [1]
AdoC(GABA)Arg6 DMMWNPT Discovery agent N.A. Investigative [4]
AdcAhxArg4Lys(biotin)-PEG-OMe DMZYJHV Discovery agent N.A. Investigative [1]
AdoC(Aun)Arg6 DMDLHAB Discovery agent N.A. Investigative [4]
Cyclic Guanosine Monophosphate DMOU93V Discovery agent N.A. Investigative [3]
AdoCGlyArg6 DMVQJP0 Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BALANOL DMDLN9E N. A. N. A. Terminated [5]
4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol DMSKJ1X Discovery agent N.A. Investigative [6]
Ro-4396686 DM5DMCH Discovery agent N.A. Investigative [7]
[3H]cAMP DMZRQU7 Discovery agent N.A. Investigative [3]
AdoC(Dpr)2AlaArg6 DM2TWSZ Discovery agent N.A. Investigative [4]
AdcAhxArg4NH(CH2)6NH2 DMSYMRJ Discovery agent N.A. Investigative [1]
AdcAhxArg4Lys-PEGOMe DMQ2C8X Discovery agent N.A. Investigative [1]
AdoC(GABA)Arg6 DMMWNPT Discovery agent N.A. Investigative [4]
AdcAhxArg4Lys(biotin)-PEG-OMe DMZYJHV Discovery agent N.A. Investigative [1]
AdoC(Aun)Arg6 DMDLHAB Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
cAMP protein kinase type II-beta (PRKAR2B) TTW4Y2M KAP3_HUMAN Inhibitor [1]
cAMP-dependent protein kinase A type I (PRKAR1A) TTNAHEX KAP0_HUMAN Inhibitor [1]

References

1 Liquid-phase synthesis of a pegylated adenosine-oligoarginine conjugate, cell-permeable inhibitor of cAMP-dependent protein kinase. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3035-9.
2 Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J Med Chem. 1992 Jan;35(1):177-84.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 Adenosine-5'-carboxylic acid peptidyl derivatives as inhibitors of protein kinases. Bioorg Med Chem Lett. 1999 May 17;9(10):1447-52.
5 Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. J Med Chem. 2005 Sep 8;48(18):5613-38. Address;
6 4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects. J Med Chem. 2006 Nov 2;49(22):6500-9.
7 Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1950-3.