General Information of Drug (ID: DM7K5GD)

Drug Name
Lutropin alfa Drug Info
Synonyms Luveris; Luveris (TN); Lutropin alfa (USAN/INN)
Indication
Disease Entry ICD 11 Status REF
Female infertility GA31.Z Approved [1]
Therapeutic Class
Fertility Agents
Cross-matching ID
TTD Drug ID
DM7K5GD

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Chorionic Gonadotropin DMFT73E Fertility disorders 5A61 Approved [3]
Choriogonadotropin alfa DMFMZ3G Female infertility GA31.Z Approved [3]
ML-04 DMQSO4L Myelodysplastic syndrome 2A37 Phase 2 [4]
Org-43902 DME0WX2 Infertility GB04 Phase 1 [5]
LDI-200 DMKMTR7 leukaemia 2A60-2B33 Discontinued in Phase 3 [6]
Human chorionic gonadotropin DMA7EFM Heart disease BA41-BA42 Terminated [6]
EP-200 DMAURX5 Solid tumour/cancer 2A00-2F9Z Investigative [6]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Luteinizing hormone receptor (LHCGR) TT2O4W9 LSHR_HUMAN Binder [2]

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Lutropin alfa. Drugs. 2008;68(11):1529-40.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4 Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of EGFR-overexpressing tumors. Nucl Med Biol. 2007 Jan;34(1):55-70.
5 First evidence of ovulation induced by oral LH agonists in healthy female volunteers of reproductive age. J Clin Endocrinol Metab. 2013 Apr;98(4):1558-66.
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).