Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7YAE0)

Drug Name

kallstroemin D Drug Info

Synonyms

kallstroemin D

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Preclinical Drug(s)

Investigative Drug(s)

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Drug(s) Targeting C-X-C chemokine receptor type 3 (CXCR3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
T487	DMZTL7H	Psoriatic disorder	EA90	Discontinued in Phase 2	[3]
JT07	DMHBWOP	Solid tumour/cancer	2A00-2F9Z	Preclinical	[4]
dioscin	DM5H2W9	Hepatic fibrosis	DB93.0	Preclinical	[2]
NBI-74330	DMURC6X	Discovery agent	N.A.	Investigative	[3]
Sch-900875	DM346KA	Inflammation	1A00-CA43.1	Investigative	[5]
hypoglaucin A	DMJKIUX	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-X-C chemokine receptor type 3 (CXCR3)	TT1UCIJ	CXCR3_HUMAN	Antagonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 843).
2	Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3. Mol Divers. 2005;9(1-3):123-9.
3	Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist. J Pharmacol Exp Ther. 2005 Jun;313(3):1263-71.
4	Clinical pipeline report, company report or official report of Jyant Technologies.
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 70).