Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM86E2P)

Drug Name
Carboxylic acid derivative 1 Drug Info
Synonyms PMID28627961-Compound-37
Indication
Disease Entry ICD 11 Status REF
Angiogenesis disorder BE2Z Patented [1]
Neoplasm 2A00-2F9Z Patented [1]
Cross-matching ID
TTD Drug ID
DM86E2P

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostaglandin E synthase (PTGES)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AAD-2004 DMG4RK0 Alzheimer disease 8A20 Phase 1 [3]
Phthalazinone derivative 1 DMNA941 N. A. N. A. Patented [2]
Benzamide derivative 18 DMD7640 N. A. N. A. Patented [2]
Betais-sulfonylamino derivative 1 DMMCDR7 N. A. N. A. Patented [2]
Benzimidazole derivative 13 DMV4DQI N. A. N. A. Patented [2]
Benzamide derivative 16 DMOAXKF N. A. N. A. Patented [2]
Imidazopyridine derivative 5 DMUKBGD N. A. N. A. Patented [2]
Imidazopyridine derivative 6 DMA0V4F N. A. N. A. Patented [2]
PMID28627961-Compound-22 DM36P7T N. A. N. A. Patented [2]
Imidazole benzamide derivative 1 DM0SOKJ Knee pain ME82 Patented [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin E synthase (PTGES) TTYLQ8V PTGES_HUMAN Inhibitor [2]

References

1 VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Sep;27(9):987-1004.
2 Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059.
3 Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2012 Sep;122(5):952-61.