Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM89RT7)

Drug Name

PTX-007011 Drug Info

Synonyms

PTX-040334; PTX-042695; Phosphopantethiene adenyltransferase inhibitors (antibacterial); Phosphopantethiene adenyltransferase inhibitors (antibacterial), PanTherix

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Terminated	[1]

Cross-matching ID

TTD Drug ID: DM89RT7

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Phosphopantetheine adenylyltransferase (PPAT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[3]
Coenzyme A	DM1I8LU	Discovery agent	N.A.	Investigative	[3]
4'-Phosphopantetheine	DMJ0A4Z	Discovery agent	N.A.	Investigative	[3]
Dephospho Coenzyme A	DMGHM1L	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphopantetheine adenylyltransferase (PPAT)	TT4YO0Z	COASY_HUMAN	Inhibitor	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018127)
2	NME DIGEST. Drug News & Perspect 2002, 15(8):519, ISSN 0214-0934.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.