Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9201K)

Drug Name

F-652 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Graft-versus-host disease	4B24	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Interleukin-22 (IL22)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fezakinumab	DMJX2P4	Psoriasis vulgaris	EA90	Phase 2	[3]
RG7880	DM452RF	Diabetic foot ulcer	BD54	Phase 2	[4]
ILV-095	DMQ01MP	Psoriasis vulgaris	EA90	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT02406651) A Phase IIa Study of Recombinant Human Interleukin-22 IgG2-Fc (F 652) in Combination With Systemic Corticosteroids for the Treatment of Newly Diagnosed Grade II-IV Lower Gastrointestinal Acute Graft-versus-Host Disease (aGVHD) in Hematopoietic Stem Cell Transplantation Recipients (HSCT). U.S.National Institutes of Health.
2	An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis. Hepatology. 2020 Aug;72(2):441-453.
3	Emerging Therapies for the Treatment of Psoriasis. Dermatol Ther (Heidelb) 2012 December; 2(1): 16.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)