Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM958C5)

Drug Name
AMB-05X Drug Info
Indication
Disease Entry ICD 11 Status REF
Idiopathic pulmonary fibrosis CB03.4 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM958C5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Macrophage colony-stimulating factor 1 receptor (CSF1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pexidartinib DMS2J0Z Tenosynovial giant cell tumour 2F7B Approved [3]
Sulfatinib DMPOTM4 Neuroendocrine cancer 2B72.1 Phase 3 [4]
ARRY-382 DM0VGDC Solid tumour/cancer 2A00-2F9Z Phase 2 [4]
BLZ-945 DMG1LVA Amyotrophic lateral sclerosis 8B60.0 Phase 2 [4]
Cabiralizumab DMGE058 Pancreatic cancer 2C10 Phase 2 [5]
FPA-008 DM3ZN6Y Autoimmune diabetes 5A10 Phase 1/2 [6]
DCC-3014 DMHW289 Solid tumour/cancer 2A00-2F9Z Phase 1/2 [4]
DCC-3014 DMHW289 Solid tumour/cancer 2A00-2F9Z Phase 1/2 [7]
PLX7486 DM0IVGU Pancreatic cancer 2C10 Phase 1 [4]
TPX-0022 DMC2IJN Solid tumour/cancer 2A00-2F9Z Phase 1 [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Macrophage colony-stimulating factor 1 receptor (CSF1R) TT7MRDV CSF1R_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT05349760) A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AMB-05X in Subjects With Idiopathic Pulmonary Fibrosis. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of AmMax Bio
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7 Clinical pipeline report, company report or official report of Deciphera Pharmaceuticals.
8 Clinical pipeline report, company report or official report of Turning Point Therapeutics.