General Information of Drug (ID: DM9BYJ0)

Drug Name
Methyl 2-amino-4-phenylthiophene-3-carboxylate Drug Info
Synonyms
methyl 2-amino-4-phenylthiophene-3-carboxylate; 67171-55-5; 2-Amino-4-phenyl-thiophene-3-carboxylic acid methyl ester; 2-Amino-4-phenylthiophene-3-carboxylic acid methyl ester; 2-amino-4-phenylthiophene-3-carboxylic acidmethyl ester; AC1LEGNM; SMR000122717; ChemDiv3_014276; MLS000523644; SCHEMBL688523; METHYL2-AMINO-4-PHENYLTHIOPHENE-3-CARBOXYLATE; CHEMBL1456242; CTK6I8713; ZINC52966; DTXSID30350681; HMS1513I20; BDBM139491; HMS2354F24; KS-00003KD2; ALBB-001671; BBL015795; SBB006989; MFCD01050444; 7878AE; STK256668; AKOS000220131; FS
Cross-matching ID
PubChem CID
685886
CAS Number
CAS 67171-55-5
TTD Drug ID
DM9BYJ0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Y-9680 DMHAVYS N. A. N. A. Patented [1]
US8889696, 39 DMKXRJ4 N. A. N. A. Patented [2]
US8889672, 252-036-001 DM8B1Q4 N. A. N. A. Patented [1]
RO-320432 DMFZ1YW N. A. N. A. Terminated [3]
LY-317644 DMM20PI N. A. N. A. Terminated [4]
RO-316233 DMAGLPW Discovery agent N.A. Investigative [5]
Bisindolylmaleimide-I DMOQJZC Discovery agent N.A. Investigative [6]
LY-326449 DMN53M4 Discovery agent N.A. Investigative [7]
[2,2':5',2'']Terthiophen-4-yl-methanol DMRQC1F Discovery agent N.A. Investigative [8]
4-[1-(4-hydroxyphenyl)-3-methyl-1-butenyl]phenol DM8IYG1 Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein kinase C zeta (PRKCZ) TTUWGRA KPCZ_HUMAN Inhibitor [1]

References

1 Compounds, formulations, and methods of protein kinase C inhibition. US8889672.
2 Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof. US8889696.
3 Bisindolylmaleimide inhibitors of protein kinase C. Further conformational restriction of a tertiary amine side chain, Bioorg. Med. Chem. Lett. 4(11):1303-1308 (1994).
4 Synthesis of bisindolylmaleimide macrocycles, Bioorg. Med. Chem. Lett. 5(18):2093-2096 (1995).
5 Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J Med Chem. 1992 Jan;35(1):177-84.
6 Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines. J Neurooncol. 2000 Apr;47(2):109-15.
7 (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H... J Med Chem. 1996 Jul 5;39(14):2664-71.
8 Novel protein kinase C inhibitors: synthesis and PKC inhibition of beta-substituted polythiophene derivatives. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2279-82.
9 Multivariate analysis by the minimum spanning tree method of the structural determinants of diphenylethylenes and triphenylacrylonitriles implicate... J Med Chem. 1992 Feb 7;35(3):573-83.