Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9KF0H)

Drug Name

Ethyl Oxo(Piperidin-1-Yl)Acetate Drug Info

Synonyms

53074-96-7; Ethyl 1-piperidineglyoxylate; Ethyl 1-piperidineoxoacetate; ETHYL OXO(PIPERIDIN-1-YL)ACETATE; ethyl 2-oxo-2-(piperidin-1-yl)acetate; ASBDXHCMVYVJQQ-UHFFFAOYSA-N; 1-Piperidineaceticacid, a-oxo-, ethyl ester; E1P; Ethyl1-piperidineglyoxylate; EINECS 258-343-9; N-ethoxalylpiperidine; 1w8m; AI3-26189; AC1L2WQF; ethyl 2-oxo-2-piperidylacetate; SCHEMBL1819086; CTK4J7020; DTXSID60201157; MolPort-001-510-784; Ethyl oxo(1-piperidinyl)acetate #; ZINC2149356; ALBB-030316; ethyl 2-oxo-2-piperidin-1-ylacetate; AKOS000444140

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 104406
CAS Number: CAS 53074-96-7
TTD Drug ID: DM9KF0H

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Rotamase A (PPIA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Proline	DMKSTWR	Malnutrition	5B50-5B71	Approved	[2]
3-[3-(3-benzyloxy-pyridin-2-yl)-ureido]-benzamide	DM60YGF	Discovery agent	N.A.	Investigative	[3]
(3r)-1-Acetyl-3-Methylpiperidine	DM49YTN	Discovery agent	N.A.	Investigative	[4]
7-AMINO-4-METHYL-CHROMEN-2-ONE	DMC8O3Z	Discovery agent	N.A.	Investigative	[1]
1-(3-benzyloxy-pyridin-2-yl)-3-phenyl-urea	DMDZAVU	Discovery agent	N.A.	Investigative	[3]
4-[3-(3-benzyloxy-pyridin-2-yl)-ureido]-benzamide	DMOPRQ7	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Rotamase A (PPIA)	TTL2ADK	PPIA_HUMAN	Inhibitor	[1]

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References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2	Mechanistic insight into the role of transition-state stabilization in cyclophilin A. J Am Chem Soc. 2009 Jan 14;131(1):147-52.
3	Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A. J Med Chem. 2006 Feb 9;49(3):900-10.
4	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.