Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMACVEI)

Drug Name
Eflapegrastim Drug Info
Synonyms SPI-2012
Indication
Disease Entry ICD 11 Status REF
Neutropenia 4B00.0 Approved [1]
Breast cancer 2C60-2C65 Phase 3 [2]
Cross-matching ID
TTD Drug ID
DMACVEI

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Granulocyte colony-stimulating factor (CSF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Efbemalenograstim DMDNJ18 Neutropenia 4B00.0 Approved [4]
Interleukin-3 DM1Y69Q Aplastic anemia 3A70 Approved [5]
Neugranin DMLRKJX Neutropenia 4B00.0 Preregistration [6]
DA-3031 DM6S4R2 Neutropenia 4B00.0 Phase 3 [7]
MK-4214 DMA25NO Neutropenia 4B00.0 Phase 3 [8]
LA-EP2006 DMI3YLK Neutropenia 4B00.0 Phase 3 [9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Granulocyte colony-stimulating factor (CSF3) TT5TQ2W CSF3_HUMAN Modulator [3]

References

1 FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761148.
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031953)
3 Company report (Sppirx)
4 Clinical pipeline report, company report or official report of Generon (Shanghai) Corporation Ltd.
5 Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. Int J Immunopharmacol. 1992 Apr;14(3):421-30.
6 Development and Characterization of a Novel Fusion Protein of a Mutated Granulocyte Colony-Stimulating Factor and Human Serum Albumin in Pichia pastoris. PLoS One. 2014; 9(12): e115840.
7 A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer.Invest New Drugs.2013 Oct;31(5):1300-6.
8 DOI: 10.1038/nbt0710-636a
9 National Cancer Institute Drug Dictionary (drug id 724518).