Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAVQR1)

Drug Name

THR-184 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Renal fibrosis	GC01	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bone morphogenetic protein 7 (BMP7)	TTKOBRA	BMP7_HUMAN	Agonist	[2]

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References

1	ClinicalTrials.gov (NCT01830920) A Study of THR-184 in Patients at Risk of Developing Cardiac Surgery Associated-Acute Kidney Injury (CSA-AKI). U.S. National Institutes of Health.
2	Perioperative THR-184 and AKI after Cardiac Surgery. J Am Soc Nephrol. 2018 Feb;29(2):670-679.