Details of the Drug

General Information of Drug (ID: DMAVQR1)

Drug Name

THR-184

Indication

Disease Entry	ICD 11	Status	REF
Renal fibrosis	GC01	Phase 2	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bone morphogenetic protein 7 (BMP7)	TTKOBRA	BMP7_HUMAN	Agonist	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01830920) A Study of THR-184 in Patients at Risk of Developing Cardiac Surgery Associated-Acute Kidney Injury (CSA-AKI). U.S. National Institutes of Health.
2	Perioperative THR-184 and AKI after Cardiac Surgery. J Am Soc Nephrol. 2018 Feb;29(2):670-679.