Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMB4GD9)

Drug Name

IONIS-GCGR-Rx Drug Info

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Glucagon receptor messenger RNA (GCGR mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-GCGR	DMHNYWP	Diabetic complication	5A2Y	Phase 2	[3]
ISIS 325568	DMEJ4B7	Type-2 diabetes	5A11	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon receptor messenger RNA (GCGR mRNA)	TTLMJSC	GLR_HUMAN	Inhibitor	[1]

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References

1	Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
4	Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.