Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBKZ4R)

Drug Name

IGN-311 Drug Info

Synonyms

HuABL-364; IGN-314; Anti-Lewis Y mAb (cancer), Igeneon

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Terminated	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Carbohydrate antigen Lewis-Y (Lewis-Y)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CAR-T cells targeting Lewis-Y	DMGI58S	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbohydrate antigen Lewis-Y (Lewis-Y)	TTV75BJ	NOUNIPROTAC	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006823)
2	IGN-311. Igeneon. Curr Opin Investig Drugs. 2005 Dec;6(12):1272-9.
3	ClinicalTrials.gov (NCT03198052) HER2/Mesothelin/Lewis-Y/PSCA/MUC1/PD-L1/CD80/86-CAR-T Cells Immunotherapy Against Cancers